Basic Information
ID: ALA4195578
Type: ADME
Description: Inhibition of CYP1A2 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4195578
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.64 | 5.18 | 5.18 |
| 504.68 | 5.71 | 5.71 |
| 518.70 | 5.96 | 5.96 |
| 518.70 | 5.96 | 5.96 |
| 506.69 | 5.68 | 5.68 |
| 476.62 | 4.79 | 4.79 |
| 483.06 | 5.83 | 5.83 |
| 492.62 | 4.71 | 4.71 |