Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measuri...

Basic Information

ID: ALA4195900

Type: Binding

Description: Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measuring reduction in [3H]thymidine incorporation preincubated for 5 days followed by [3H]thymidine addition measured after 18 hrs by liquid scintillation counting method

Format: BAO_0000019

Organism: Homo sapiens

Target: PI4-kinase beta subunit(ALA3268)

Document: ALA4190408

Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measuring reduction in [3H]thymidine incorporation preincubated for 5 days followed by [3H]thymidine addition measured after 18 hrs by liquid scintillation counting method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4195900

IC50

Total(42)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
389.89	1.42	1.42
481.97	3.11	3.11
411.51	2.77	2.77
470.99	4.35	4.35
386.44	1.43	1.43
400.47	1.73	1.73
399.48	2.42	2.42
413.51	2.73	2.73
413.51	2.73	2.73
399.48	2.42	2.42
399.48	2.42	2.42
462.54	3.09	3.09
369.45	2.33	2.33
380.44	1.28	1.28
446.54	3.39	3.39
355.43	2.02	2.02
399.48	2.34	2.34
414.50	2.12	2.12
413.51	2.81	2.81
413.51	2.81	2.81
410.48	2.01	2.01
369.45	2.33	2.33
461.55	3.70	3.70
369.45	2.33	2.33
404.88	2.05	2.05
410.48	2.01	2.01
445.91	3.88	3.88
411.49	2.56	2.56
380.44	1.51	1.51
413.51	2.81	2.81
399.48	1.71	1.71
439.42	2.92	2.92
412.52	3.33	3.33
413.51	2.73	2.73
497.40	3.70	3.70
414.49	1.58	1.58
410.48	2.01	2.01
400.47	1.73	1.73
385.45	2.03	2.03
411.49	2.56	2.56
379.45	2.11	2.11
356.42	1.42	1.42