Basic Information
ID: ALA4195900
Type: Binding
Description: Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measuring reduction in [3H]thymidine incorporation preincubated for 5 days followed by [3H]thymidine addition measured after 18 hrs by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4195900
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.89 | 1.42 | 1.42 |
| 481.97 | 3.11 | 3.11 |
| 411.51 | 2.77 | 2.77 |
| 470.99 | 4.35 | 4.35 |
| 386.44 | 1.43 | 1.43 |
| 400.47 | 1.73 | 1.73 |
| 399.48 | 2.42 | 2.42 |
| 413.51 | 2.73 | 2.73 |
| 413.51 | 2.73 | 2.73 |
| 399.48 | 2.42 | 2.42 |
| 399.48 | 2.42 | 2.42 |
| 462.54 | 3.09 | 3.09 |
| 369.45 | 2.33 | 2.33 |
| 380.44 | 1.28 | 1.28 |
| 446.54 | 3.39 | 3.39 |
| 355.43 | 2.02 | 2.02 |
| 399.48 | 2.34 | 2.34 |
| 414.50 | 2.12 | 2.12 |
| 413.51 | 2.81 | 2.81 |
| 413.51 | 2.81 | 2.81 |
| 410.48 | 2.01 | 2.01 |
| 369.45 | 2.33 | 2.33 |
| 461.55 | 3.70 | 3.70 |
| 369.45 | 2.33 | 2.33 |
| 404.88 | 2.05 | 2.05 |
| 410.48 | 2.01 | 2.01 |
| 445.91 | 3.88 | 3.88 |
| 411.49 | 2.56 | 2.56 |
| 380.44 | 1.51 | 1.51 |
| 413.51 | 2.81 | 2.81 |
| 399.48 | 1.71 | 1.71 |
| 439.42 | 2.92 | 2.92 |
| 412.52 | 3.33 | 3.33 |
| 413.51 | 2.73 | 2.73 |
| 497.40 | 3.70 | 3.70 |
| 414.49 | 1.58 | 1.58 |
| 410.48 | 2.01 | 2.01 |
| 400.47 | 1.73 | 1.73 |
| 385.45 | 2.03 | 2.03 |
| 411.49 | 2.56 | 2.56 |
| 379.45 | 2.11 | 2.11 |
| 356.42 | 1.42 | 1.42 |