Basic Information
ID: ALA4195907
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes assessed as decrease in midazolam 1-hydroxylation by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4195907
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.97 | 3.11 | 3.11 |
| 399.48 | 2.42 | 2.42 |
| 413.51 | 2.73 | 2.73 |
| 413.51 | 2.73 | 2.73 |
| 399.48 | 2.42 | 2.42 |
| 399.48 | 2.42 | 2.42 |
| 462.54 | 3.09 | 3.09 |
| 446.54 | 3.39 | 3.39 |
| 414.50 | 2.12 | 2.12 |
| 413.51 | 2.81 | 2.81 |
| 413.51 | 2.81 | 2.81 |
| 410.48 | 2.01 | 2.01 |
| 461.55 | 3.70 | 3.70 |
| 410.48 | 2.01 | 2.01 |
| 411.49 | 2.56 | 2.56 |
| 413.51 | 2.81 | 2.81 |
| 412.52 | 3.33 | 3.33 |
| 413.51 | 2.73 | 2.73 |
| 385.45 | 2.03 | 2.03 |
| 411.49 | 2.56 | 2.56 |