Basic Information
ID: ALA4196286
Type: Binding
Description: Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated for 60 mins followed by substrate addition and measured after 25 mins by ELISA
Format: BAO_0000357
Organism: Mus musculus
Target: Serine/threonine-protein kinase B-raf(ALA2331061)
Document: ALA4196002
Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated for 60 mins followed by substrate addition and measured after 25 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4196286
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 390.40 | 4.08 | 4.08 |
| 322.80 | 4.33 | 4.33 |
| 308.77 | 4.03 | 4.03 |
| 342.83 | 3.46 | 3.46 |
| 370.37 | 4.95 | 4.95 |
| 328.80 | 3.15 | 3.15 |