Basic Information
ID: ALA4196386
Type: ADME
Description: Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells at 10 uM incubated for 30 mins by luciferase assay relative to control
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Activity Charts
Bioactivity
Activity Types for Assay ALA4196386
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 258.14 | 2.03 | 2.03 |
| 248.14 | 2.57 | 2.57 |
| 272.38 | 2.48 | 2.48 |
| 224.25 | 1.17 | 1.17 |
| 211.25 | 0.26 | 0.26 |
| 209.27 | 0.86 | 0.86 |
| 225.27 | 0.57 | 0.57 |
| 195.25 | 0.56 | 0.56 |
| 195.25 | 0.56 | 0.56 |
| 239.30 | 0.87 | 0.87 |
| 269.33 | 0.88 | 0.88 |
| 205.29 | 1.52 | 1.52 |
| 169.21 | 0.45 | 0.45 |
| 208.29 | 0.83 | 0.83 |
| 224.25 | 0.76 | 0.76 |
| 255.35 | 2.52 | 2.52 |
| 225.34 | 1.58 | 1.58 |
| 230.30 | 1.40 | 1.40 |
| 299.36 | 2.25 | 2.25 |
| 315.40 | 2.54 | 2.54 |
| 239.30 | 0.87 | 0.87 |
| 194.26 | 0.44 | 0.44 |
| 209.27 | 0.95 | 0.95 |
| 354.26 | 3.74 | 3.74 |
| 199.30 | 1.22 | 1.22 |
| 223.25 | -3.12 | -3.12 |
| 235.34 | 2.07 | 2.07 |
| 255.35 | 2.52 | 2.52 |