Assay Report Card

Basic Information

ID: ALA4196390

Type: Functional

Description: Potentiation of methotrexate-induced antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream form assessed as dose reduction index for methotrexate at EC50 after 72 hrs by resazurin dye-based assay

Organism: Trypanosoma brucei

Strain: Lister 427

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
315.402.542.54
354.263.743.74