Basic Information
ID: ALA4197290
Type: Binding
Description: Inhibition of DNA topoisomerase-1 (unknown origin) up to 40 uM using supercoiled pBR322 DNA as substrate preincubated with enzyme followed by substrate addition measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase I(ALA1781)
Document: ALA4196027
Inhibition of DNA topoisomerase-1 (unknown origin) up to 40 uM using supercoiled pBR322 DNA as substrate preincubated with enzyme followed by substrate addition measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4197290
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 638.58 | 2.23 | 2.23 |
| 654.58 | 1.14 | 1.14 |