Basic Information
ID: ALA4197379
Type: Binding
Description: Inhibition of MD2 in C57BL/6 mouse primary peritoneal macrophages assessed as reduction in LPS-induced TLR4 activation-mediated NF-kB signaling by measuring reduction in IkB degradation at 5 to 10 uM preincubated for 30 mins followed by LPS addition measured after 20 mins by Western blot analysis
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4197379
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.53 | 3.72 | 3.72 |
| 456.49 | 3.80 | 3.80 |