Basic Information
ID: ALA4197382
Type: Binding
Description: Inhibition of MD2 in rat RAW264.7 cells harboring NF-kB-luc assessed as inhibition of LPS-induced TLR4 activation-mediated NF-kB transcriptional activity at 2.5 uM preincubated with cells followed by LPS addition measured after 6 hrs by luciferase reporter gene assay
Organism: Rattus norvegicus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA4197382
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.53 | 3.72 | 3.72 |
| 456.49 | 3.80 | 3.80 |