Basic Information
ID: ALA4197602
Type: Binding
Description: Inhibition of Leucyl-tRNA synthetase in Escherichia coli K-12 BW28357 S30 extract assessed as reduction in tRNA aminoacylation at 2.5 uM preincubated for 5 mins followed by Escherichia coli tRNA and 14C-labeled leucine addition measured after 5 mins by liquid scintillation counting method relative to control
Organism: Escherichia coli K-12
Strain: BW28357
Activity Charts
Bioactivity
Activity Types for Assay ALA4197602
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.49 | -2.22 | -2.22 |
| 458.50 | -1.62 | -1.62 |