Assay Report Card

Basic Information

ID: ALA4197603

Type: Binding

Description: Inhibition of Tyrosyl-tRNA synthetase in Escherichia coli K-12 BW28357 S30 extract assessed as reduction in tRNA aminoacylation at 2.5 uM preincubated for 5 mins followed by Escherichia coli tRNA and 14C-labeled tyrosine addition measured after 5 mins by liquid scintillation counting method relative to control

Organism: Escherichia coli K-12

Strain: BW28357

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
509.50-2.32-2.32
508.51-1.71-1.71