Basic Information
ID: ALA4198189
Type: Binding
Description: Inhibition of N-terminal GST-tagged full length recombinant human PDE5A1 catalytic domain expressed in Baculovirus infected Sf9 insect cells using FAM-cGMP as substrate after 1 hr by fluorescence polarization assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4198189
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.59 | 1.61 | 1.61 |
| 451.56 | 5.11 | 5.11 |
| 358.40 | 3.58 | 3.58 |
| 451.56 | 5.11 | 5.11 |
| 480.59 | 5.73 | 5.73 |
| 453.37 | 4.81 | 4.81 |
| 435.49 | 4.65 | 4.65 |
| 469.55 | 5.25 | 5.25 |
| 373.48 | 4.66 | 4.66 |
| 451.56 | 5.11 | 5.11 |
| 435.49 | 4.65 | 4.65 |
| 450.57 | 5.72 | 5.72 |
| 451.56 | 5.11 | 5.11 |
| 510.62 | 5.74 | 5.74 |
| 451.56 | 5.11 | 5.11 |
| 435.49 | 4.65 | 4.65 |
| 374.47 | 4.05 | 4.05 |