Basic Information
ID: ALA4198470
Type: Binding
Description: Displacement of FITC-JQ1 from His6-tagged BRD4 bromodomain-1 (unknown origin) expressed in Escherichia coli BL21(DE3) after 4 hrs by fluorescence anisotropy method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4198470
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 521.67 | 3.56 | 3.56 |
| 423.90 | 3.66 | 3.66 |
| 457.00 | 5.53 | 5.53 |
| 349.43 | 3.58 | 3.58 |
| 349.43 | 3.58 | 3.58 |
| 341.46 | 3.08 | 3.08 |
| 405.54 | 5.06 | 5.06 |
| 341.46 | 3.03 | 3.03 |
| 363.46 | 3.89 | 3.89 |
| 369.51 | 3.82 | 3.82 |
| 375.47 | 3.44 | 3.44 |
| 355.48 | 3.43 | 3.43 |
| 376.46 | 2.93 | 2.93 |
| 367.45 | 2.62 | 2.62 |
| 353.40 | 3.41 | 3.41 |
| 355.48 | 3.33 | 3.33 |
| 335.41 | 3.27 | 3.27 |
| 399.47 | 2.14 | 2.14 |
| 369.51 | 3.67 | 3.67 |
| 363.46 | 3.61 | 3.61 |
| 379.44 | 3.36 | 3.36 |
| 377.49 | 4.00 | 4.00 |
| 363.46 | 3.26 | 3.26 |
| 375.47 | 3.61 | 3.61 |
| 347.46 | 3.58 | 3.58 |
| 367.42 | 3.72 | 3.72 |
| 361.45 | 3.22 | 3.22 |
| 327.43 | 2.69 | 2.69 |
| 353.40 | 3.41 | 3.41 |
| 349.43 | 3.58 | 3.58 |
| 350.42 | 2.78 | 2.78 |
| 375.47 | 3.53 | 3.53 |
| 375.47 | 3.53 | 3.53 |
| 349.43 | 3.30 | 3.30 |
| 369.85 | 3.93 | 3.93 |
| 389.50 | 4.00 | 4.00 |
| 365.43 | 3.28 | 3.28 |
| 376.46 | 2.93 | 2.93 |
| 377.49 | 4.36 | 4.36 |
| 391.52 | 4.67 | 4.67 |
| 362.43 | 2.62 | 2.62 |
| 365.43 | 3.28 | 3.28 |
| 389.50 | 3.92 | 3.92 |
| 390.49 | 3.32 | 3.32 |