Basic Information
ID: ALA4198913
Type: Binding
Description: Inhibition of full length human recombinant N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using cGMP as substrate after 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4198913
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 453.52 | 3.52 | 3.52 |
| 462.51 | 3.54 | 3.54 |
| 479.51 | 3.52 | 3.52 |
| 491.55 | 3.39 | 3.39 |
| 461.52 | 3.39 | 3.39 |
| 453.54 | 3.45 | 3.45 |
| 453.54 | 3.45 | 3.45 |
| 451.53 | 3.36 | 3.36 |
| 491.55 | 3.53 | 3.53 |
| 477.52 | 3.37 | 3.37 |
| 479.51 | 3.52 | 3.52 |
| 447.50 | 3.53 | 3.53 |
| 465.55 | 3.75 | 3.75 |
| 467.55 | 3.45 | 3.45 |
| 477.52 | 2.88 | 2.88 |
| 475.55 | 3.31 | 3.31 |
| 461.52 | 3.45 | 3.45 |
| 467.55 | 3.52 | 3.52 |
| 451.48 | 2.98 | 2.98 |
| 491.55 | 3.39 | 3.39 |
| 447.50 | 3.46 | 3.46 |
| 481.53 | 3.09 | 3.09 |
| 461.52 | 3.38 | 3.38 |
| 453.54 | 3.45 | 3.45 |
| 454.53 | 2.40 | 2.40 |