Assay Report Card

Basic Information

ID: ALA4198919

Type: ADME

Description: Inhibition of class-1 HDAC in human SH-SY5Y cells assessed as induction of AcH3K9 level at 100 nM after 2 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: SH-SY5Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
264.322.472.47
389.412.212.21
474.591.611.61
488.612.072.07
335.412.802.80
453.523.523.52
479.513.523.52
461.523.393.39
453.543.453.45
479.513.523.52
447.503.533.53
467.553.453.45
475.553.313.31
461.523.453.45
467.553.523.52
447.503.463.46
461.523.383.38