Basic Information
ID: ALA4198924
Type: Binding
Description: Inhibition of PDE5 in human SH-SY5Y cells assessed as induction of phosphorylated CREB level at 500 nM after 2 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA4198924
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 389.41 | 2.21 | 2.21 |
| 474.59 | 1.61 | 1.61 |
| 488.61 | 2.07 | 2.07 |
| 335.41 | 2.80 | 2.80 |
| 453.52 | 3.52 | 3.52 |
| 479.51 | 3.52 | 3.52 |
| 461.52 | 3.39 | 3.39 |
| 453.54 | 3.45 | 3.45 |
| 479.51 | 3.52 | 3.52 |
| 447.50 | 3.53 | 3.53 |
| 467.55 | 3.45 | 3.45 |
| 475.55 | 3.31 | 3.31 |
| 461.52 | 3.45 | 3.45 |
| 467.55 | 3.52 | 3.52 |
| 447.50 | 3.46 | 3.46 |
| 461.52 | 3.38 | 3.38 |