Assay Report Card

Basic Information

ID: ALA4199232

Type: Functional

Description: Activation of ULK1-induced cytoprotective autophagy in MPTP-treated C57BL/6 mouse striatum assessed SQSTM1/p62 expression levels at 20 to 80 mg/kg/day, po via gavage administered 2 days before first injection of MPTP measured after 5 days post last injection of MPTP in absence of 3-MA by Western blot analysis relative to control

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
533.446.676.67