Basic Information
ID: ALA4199724
Type: Functional
Description: Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular cAMP accumulation preincubated for 10 mins followed by forskolin stimulation measured after 10 to 60 mins by ELISA based chemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4199724
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.46 | 3.99 | 3.99 |
| 568.95 | 6.10 | 6.10 |
| 462.55 | 4.91 | 4.91 |
| 550.57 | 6.16 | 6.16 |
| 477.59 | 5.73 | 5.73 |
| 504.46 | 4.75 | 4.75 |
| 534.51 | 5.45 | 5.45 |
| 534.51 | 5.45 | 5.45 |
| 362.47 | 4.43 | 4.43 |
| 476.57 | 5.30 | 5.30 |
| 436.48 | 4.16 | 4.16 |
| 438.46 | 3.99 | 3.99 |
| 550.96 | 5.96 | 5.96 |
| 448.52 | 4.52 | 4.52 |
| 502.49 | 4.92 | 4.92 |
| 432.52 | 4.41 | 4.41 |