Basic Information
ID: ALA4200192
Type: Binding
Description: Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4200192
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 345.40 | 5.16 | 5.16 |
| 351.79 | 5.20 | 5.20 |
| 386.24 | 5.85 | 5.85 |
| 342.36 | 4.42 | 4.42 |
| 342.36 | 4.42 | 4.42 |
| 369.78 | 5.34 | 5.34 |
| 304.35 | 3.91 | 3.91 |
| 331.38 | 4.85 | 4.85 |
| 335.34 | 4.68 | 4.68 |
| 331.38 | 4.85 | 4.85 |
| 316.36 | 4.28 | 4.28 |
| 401.34 | 5.44 | 5.44 |
| 351.79 | 5.20 | 5.20 |
| 327.39 | 4.95 | 4.95 |
| 342.36 | 4.42 | 4.42 |
| 353.33 | 4.82 | 4.82 |
| 347.37 | 4.55 | 4.55 |
| 335.34 | 4.68 | 4.68 |
| 317.35 | 4.55 | 4.55 |
| 401.34 | 5.44 | 5.44 |
| 330.39 | 4.29 | 4.29 |
| 401.34 | 5.44 | 5.44 |
| 351.79 | 5.20 | 5.20 |
| 335.34 | 4.68 | 4.68 |
| 347.37 | 4.55 | 4.55 |
| 394.43 | 5.61 | 5.61 |
| 347.37 | 4.55 | 4.55 |
| 358.36 | 4.69 | 4.69 |
| 333.42 | 5.01 | 5.01 |
| 345.40 | 5.11 | 5.11 |
| 331.38 | 4.85 | 4.85 |