Basic Information
ID: ALA4200544
Type: Binding
Description: Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Target: GRIA1/CACNG8(ALA4296110)
Document: ALA4196161
Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4200544
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.11 | 3.23 | 3.23 |
| 342.70 | 4.10 | 4.10 |
| 237.30 | 3.47 | 3.47 |
| 283.72 | 3.24 | 3.24 |
| 327.69 | 4.40 | 4.40 |
| 274.71 | 3.19 | 3.19 |
| 258.71 | 3.49 | 3.49 |
| 238.29 | 3.14 | 3.14 |
| 341.72 | 4.71 | 4.71 |
| 345.73 | 4.81 | 4.81 |
| 329.66 | 4.34 | 4.34 |
| 279.13 | 3.83 | 3.83 |
| 223.28 | 3.16 | 3.16 |
| 328.68 | 4.08 | 4.08 |
| 324.71 | 3.81 | 3.81 |
| 284.75 | 4.05 | 4.05 |
| 345.68 | 4.54 | 4.54 |
| 269.69 | 3.05 | 3.05 |