Basic Information
ID: ALA4200634
Type: ADME
Description: Inhibition of S-3969-stimulated recombinant human ENaC alpha subunit expressed in HEK293 cells at 10 uM preincubated for 5 mins followed by S-3969 stimulation by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4200634
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.63 | -1.08 | -1.08 |
| 311.78 | 0.72 | 0.72 |
| 421.43 | 2.75 | 2.75 |
| 355.41 | 0.52 | 0.52 |
| 393.45 | 2.48 | 2.48 |
| 392.47 | 2.21 | 2.21 |