Basic Information
ID: ALA4200880
Type: Functional
Description: Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assay
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4200880
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 697.68 | 1.71 | 1.71 |
| 618.61 | 5.61 | 5.61 |
| 448.37 | 4.92 | 4.92 |
| 761.72 | 2.63 | 2.63 |
| 762.71 | 2.02 | 2.02 |
| 665.62 | 1.46 | 1.46 |
| 649.21 | 0.72 | 0.72 |
| 460.41 | 4.60 | 4.60 |
| 430.38 | 4.97 | 4.97 |
| 464.42 | 4.59 | 4.59 |
| 725.74 | 2.49 | 2.49 |
| 725.69 | 2.24 | 2.24 |
| 448.42 | 4.88 | 4.88 |
| 444.41 | 5.36 | 5.36 |
| 740.75 | 2.33 | 2.33 |
| 448.37 | 4.92 | 4.92 |
| 539.87 | 4.84 | 4.84 |
| 761.72 | 2.63 | 2.63 |
| 548.54 | 5.68 | 5.68 |
| 670.60 | 5.03 | 5.03 |
| 403.35 | 5.50 | 5.50 |
| 762.71 | 2.02 | 2.02 |
| 697.68 | 1.71 | 1.71 |
| 765.72 | 1.36 | 1.36 |
| 854.85 | 1.84 | 1.84 |
| 389.33 | 4.94 | 4.94 |
| 598.55 | 6.16 | 6.16 |
| 666.67 | 3.22 | 3.22 |
| 649.64 | 5.07 | 5.07 |
| 444.41 | 5.36 | 5.36 |
| 781.78 | 2.08 | 2.08 |
| 719.69 | 3.03 | 3.03 |
| 711.71 | 2.15 | 2.15 |
| 416.35 | 4.58 | 4.58 |
| 751.69 | 2.22 | 2.22 |
| 476.47 | 5.66 | 5.66 |
| 1049.04 | ||
| 407.37 | 5.10 | 5.10 |
| 446.38 | 3.94 | 3.94 |
| 677.65 | 5.03 | 5.03 |
| 454.04 | 5.11 | 5.11 |
| 419.35 | 5.16 | 5.16 |
| 533.57 | 5.56 | 5.56 |
| 1673.68 | ||
| 446.38 | 4.21 | 4.21 |
| 769.75 | 1.95 | 1.95 |
| 742.72 | 1.78 | 1.78 |
| 430.38 | 4.97 | 4.97 |
| 683.66 | 1.37 | 1.37 |
| 680.70 | 3.61 | 3.61 |
| 444.41 | 5.36 | 5.36 |
| 683.61 | 1.41 | 1.41 |
| 433.38 | 5.41 | 5.41 |
| 761.73 | 2.63 | 2.63 |
| 460.41 | 4.60 | 4.60 |
| 481.97 | 5.25 | 5.25 |
| 735.69 | 1.29 | 1.29 |
| 433.38 | 5.55 | 5.55 |
| 762.71 | 2.02 | 2.02 |
| 478.45 | 4.38 | 4.38 |
| 761.77 | 4.20 | 4.20 |
| 446.38 | 3.94 | 3.94 |
| 726.72 | 1.94 | 1.94 |
| 462.45 | 4.93 | 4.93 |
| 466.36 | 5.22 | 5.22 |
| 740.75 | 2.28 | 2.28 |
| 739.71 | 5.06 | 5.06 |