Basic Information
ID: ALA4200947
Type: Binding
Description: Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10 mins followed by substrate addition measured over 5 mins by TR-FRET assay
Format: BAO_0000357
Organism: Mus musculus
Target: Insulin-degrading enzyme(ALA3232680)
Document: ALA4196173
Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10 mins followed by substrate addition measured over 5 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4200947
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1422.72 | ||
| 1849.15 | ||
| 1518.78 | ||
| 1306.49 | ||
| 991.16 | -1.41 | -1.41 |
| 1837.16 | ||
| 1951.27 | ||
| 1678.98 | ||
| 1203.45 | ||
| 866.05 | -1.66 | -1.66 |
| 1890.16 | ||
| 1962.23 | ||
| 1678.98 | ||
| 1598.85 |