Assay Report Card

Basic Information

ID: ALA4201028

Type: Binding

Description: Inhibition of ACK1 in mouse BA/F3 cells harboring NRAS-G12D mutant assessed as reduction in P70S6K1 phosphorylation at Thr421/Ser424 at 1 uM after 2 hrs by Western blot analysis

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
456.434.214.21
673.705.555.55
673.746.226.22
550.555.425.42