Basic Information
ID: ALA4201034
Type: Binding
Description: Inhibition of GCK in human OCI-AML3 cells harboring NRAS Q61L mutant assessed as reduction in JNK phosphorylation at T183/Y185 at 1 uM after 2 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4201034
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.43 | 4.21 | 4.21 |
| 673.70 | 5.55 | 5.55 |
| 673.74 | 6.22 | 6.22 |
| 550.55 | 5.42 | 5.42 |