ID: ALA4201091
Type: Functional
Description: Antileukemic activity against mouse BA/F3 cells harboring NRAS-G12D mutant allografted in immunodeficient mouse assessed as median survival time at 15 mg/kg/day, po qd administered on day 6 post implantation (Rvb = 23 days)
Organism: Mus musculus
Cell type: BaF3
Bioactivity
Activity Types for Assay ALA4201091
MSD
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
456.43 | 4.21 | 4.21 |