Assay Report Card

Basic Information

ID: ALA4201092

Type: Functional

Description: Antileukemic activity against mouse BA/F3 cells harboring NRAS-G12D mutant allografted in immunodeficient mouse assessed as median survival time at 25 mg/kg/day, po qd administered on day 6 post implantation (Rvb = 23 days)

Organism: Mus musculus

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
456.434.214.21