Assay Report Card

Basic Information

ID: ALA4201093

Type: Functional

Description: Antileukemic activity against human OCI-AML3 cells harboring NRAS-Q61L mutant xenografted in immunodeficient mouse assessed as tumor volume at 8 mg/kg/day, po qd administered on day 21 post implantation measured on day 20 post implantation (Rvb = 100%)

Organism: Homo sapiens

Cell type: OCI-AML-3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
547.546.086.08