Basic Information
ID: ALA4201094
Type: Functional
Description: Antileukemic activity against human OCI-AML3 cells harboring NRAS-Q61L mutant xenografted in immunodeficient mouse assessed as tumor volume at 15 mg/kg/day, po qd administered on day 21 post implantation measured on day 20 post dose (Rvb = 100%)
Organism: Homo sapiens
Cell type: OCI-AML-3
Activity Charts
Bioactivity
Activity Types for Assay ALA4201094
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.43 | 4.21 | 4.21 |