Basic Information
ID: ALA4201109
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB E129A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins
Format: BAO_0000019
Organism: Mycobacterium tuberculosis H37Rv
Target: Phosphotyrosine-protein phosphatase PTPB(ALA4540)
Document: ALA4196176
Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB E129A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4201109
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 385.42 | 5.70 | 5.70 |
| 410.26 | 6.68 | 6.68 |
| 357.37 | 5.08 | 5.08 |
| 436.81 | 5.64 | 5.64 |
| 426.26 | 6.39 | 6.39 |