Basic Information
ID: ALA4201165
Type: Binding
Description: Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4201165
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.66 | 6.50 | 6.50 |
| 426.73 | 8.48 | 8.48 |
| 424.71 | 8.69 | 8.69 |
| 468.77 | 9.05 | 9.05 |
| 457.79 | 7.85 | 7.85 |
| 439.73 | 8.95 | 8.95 |
| 444.74 | 7.67 | 7.67 |
| 400.65 | 6.71 | 6.71 |
| 544.82 | 8.09 | 8.09 |
| 462.73 | 7.62 | 7.62 |
| 443.76 | 7.64 | 7.64 |
| 442.73 | 7.88 | 7.88 |
| 425.75 | 8.45 | 8.45 |
| 460.74 | 6.89 | 6.89 |
| 442.73 | 7.45 | 7.45 |
| 457.74 | 7.18 | 7.18 |
| 440.76 | 9.13 | 9.13 |
| 492.74 | 6.34 | 6.34 |
| 462.73 | 7.62 | 7.62 |
| 402.66 | 6.51 | 6.51 |
| 453.76 | 9.12 | 9.12 |
| 460.74 | 6.64 | 6.64 |
| 471.77 | 8.32 | 8.32 |
| 502.78 | 7.78 | 7.78 |
| 428.75 | 8.56 | 8.56 |
| 458.73 | 6.85 | 6.85 |
| 462.76 | 6.72 | 6.72 |
| 473.74 | 7.35 | 7.35 |
| 606.89 | 5.50 | 5.50 |
| 415.66 | 6.97 | 6.97 |
| 460.74 | 6.64 | 6.64 |
| 442.73 | 7.69 | 7.69 |
| 489.74 | 5.87 | 5.87 |
| 458.73 | 6.85 | 6.85 |
| 457.74 | 8.14 | 8.14 |
| 458.77 | 8.33 | 8.33 |
| 474.73 | 6.82 | 6.82 |
| 442.73 | 7.45 | 7.45 |
| 486.78 | 8.24 | 8.24 |