Assay Report Card

Basic Information

ID: ALA4201370

Type: Binding

Description: Binding affinity to SAP155 in human GM18453 cells harboring NPC1 mutant assessed as restoration of cholesterol trafficking at 50 nM after 48 hrs by filipin-staining based fluorescence microscopic analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
452.634.454.45
438.614.364.36
450.624.664.66
494.675.025.02