Basic Information
ID: ALA4201374
Type: Binding
Description: Binding affinity to SAP155 in human GM18407 cells harboring NPC1 R404Q/M1142T mutant assessed as restoration of cholesterol trafficking at 0.001 to 5 uM after 48 hrs by filipin-staining based fluorescence microscopic analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4201374
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.63 | 4.45 | 4.45 |
| 438.61 | 4.36 | 4.36 |
| 450.62 | 4.66 | 4.66 |
| 494.67 | 5.02 | 5.02 |