Basic Information
ID: ALA4201550
Type: Binding
Description: Modulation of human ABCB1 expressed in mouse L5178Y cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring combination index at ED50 measured after 48 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Target: P-glycoprotein 1(ALA4302)
Document: ALA4196198
Modulation of human ABCB1 expressed in mouse L5178Y cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring combination index at ED50 measured after 48 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4201550
CI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.44 | 3.77 | 3.77 |
| 314.43 | 3.98 | 3.98 |
| 329.44 | 4.24 | 4.24 |
| 433.55 | 5.62 | 5.62 |
| 371.48 | 4.33 | 4.33 |
| 458.73 | 6.56 | 6.56 |
| 423.51 | 5.22 | 5.22 |
| 399.53 | 5.11 | 5.11 |
| 439.58 | 5.69 | 5.69 |