Basic Information
ID: ALA4201755
Type: Binding
Description: Activation of SOS1 in human HeLa cells expressing wild type KRAS assessed as induction of ERK1/2 T202/Y204 phosphorylation incubated for 30 mins by In-cell Western assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4201755
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.43 | 6.22 | 6.22 |
| 303.77 | 4.08 | 4.08 |
| 344.82 | 3.29 | 3.29 |
| 492.00 | 4.25 | 4.25 |
| 463.95 | 3.63 | 3.63 |
| 372.88 | 3.90 | 3.90 |
| 493.03 | 5.48 | 5.48 |
| 448.93 | 4.05 | 4.05 |
| 483.04 | 3.66 | 3.66 |
| 483.42 | 6.22 | 6.22 |
| 479.00 | 4.91 | 4.91 |
| 471.02 | 3.66 | 3.66 |
| 471.02 | 3.83 | 3.83 |
| 476.99 | 4.67 | 4.67 |
| 464.98 | 4.67 | 4.67 |
| 466.99 | 4.91 | 4.91 |
| 372.88 | 3.90 | 3.90 |