Basic Information
ID: ALA4201827
Type: Binding
Description: Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4201827
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.42 | 3.21 | 3.21 |
| 430.51 | 4.39 | 4.39 |
| 430.51 | 4.39 | 4.39 |
| 430.51 | 3.00 | 3.00 |
| 498.51 | 5.50 | 5.50 |
| 426.48 | 3.68 | 3.68 |
| 403.44 | 3.13 | 3.13 |
| 402.45 | 3.69 | 3.69 |
| 430.51 | 4.01 | 4.01 |
| 324.34 | 1.99 | 1.99 |
| 401.47 | 3.27 | 3.27 |
| 458.52 | 3.29 | 3.29 |
| 417.47 | 3.40 | 3.40 |
| 402.45 | 4.07 | 4.07 |
| 450.93 | 4.66 | 4.66 |
| 413.48 | 2.05 | 2.05 |
| 440.50 | 3.98 | 3.98 |
| 444.54 | 4.82 | 4.82 |
| 483.49 | 4.51 | 4.51 |
| 387.44 | 2.96 | 2.96 |
| 417.47 | 3.40 | 3.40 |
| 431.45 | 2.38 | 2.38 |
| 417.47 | 3.40 | 3.40 |
| 420.43 | 2.58 | 2.58 |
| 430.51 | 4.56 | 4.56 |
| 416.48 | 3.93 | 3.93 |
| 458.52 | 3.29 | 3.29 |
| 450.93 | 4.66 | 4.66 |
| 287.32 | 1.99 | 1.99 |
| 440.50 | 3.98 | 3.98 |
| 203.24 | 2.19 | 2.19 |
| 484.48 | 5.11 | 5.11 |
| 440.50 | 3.98 | 3.98 |
| 444.54 | 4.74 | 4.74 |
| 407.47 | 3.04 | 3.04 |
| 354.41 | 1.52 | 1.52 |
| 417.47 | 3.40 | 3.40 |
| 400.46 | 2.20 | 2.20 |
| 484.48 | 4.93 | 4.93 |
| 417.47 | 3.33 | 3.33 |
| 416.48 | 4.00 | 4.00 |
| 401.47 | 3.27 | 3.27 |
| 457.54 | 2.86 | 2.86 |