Basic Information
ID: ALA4202145
Type: Binding
Description: Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition and measured after 6 mins
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4202145
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 395.43 | 2.42 | 2.42 |
| 149.24 | 1.84 | 1.84 |
| 608.69 | 4.17 | 4.17 |
| 337.46 | 4.24 | 4.24 |
| 347.50 | 3.81 | 3.81 |
| 439.49 | 2.50 | 2.50 |
| 489.49 | 3.38 | 3.38 |
| 464.57 | 2.42 | 2.42 |
| 439.49 | 2.50 | 2.50 |
| 319.45 | 3.03 | 3.03 |
| 421.50 | 2.36 | 2.36 |
| 427.53 | 2.42 | 2.42 |
| 489.49 | 3.38 | 3.38 |
| 497.60 | 4.03 | 4.03 |
| 479.53 | 2.13 | 2.13 |
| 439.49 | 2.50 | 2.50 |
| 435.52 | 2.67 | 2.67 |
| 493.56 | 2.54 | 2.54 |