Basic Information
ID: ALA4202177
Type: Binding
Description: Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents pre-incubated for 5 mins prior to acetyl choline pulse at -70 mV potential by two-electrode voltage clamp assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4202177
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1489.82 | ||
| 1517.83 | ||
| 1489.82 | ||
| 1531.85 | ||
| 1549.92 | ||
| 1503.84 | ||
| 1517.83 | ||
| 1558.93 | ||
| 1558.93 | ||
| 1515.90 | ||
| 1473.82 | ||
| 1539.88 | ||
| 1565.92 | ||
| 1530.91 | ||
| 1487.84 |