Basic Information
ID: ALA4219406
Type: Binding
Description: Induction of CRBN/DDB1-mediated BRD4 protein degradation in human NCI-H661 cells assessed as drug level causing 50% cellular protein depletion incubated for 4 hrs by MSD assay
Organism: Homo sapiens
Cell type: NCI-H661
Activity Charts
Bioactivity
Activity Types for Assay ALA4219406
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 785.28 | 3.68 | 3.68 |
| 781.25 | 3.58 | 3.58 |
| 869.36 | 3.61 | 3.61 |
| 825.31 | 3.59 | 3.59 |
| 1039.69 | ||
| 957.47 | 3.64 | 3.64 |
| 995.63 | 5.21 | 5.21 |
| 1002.66 | ||
| 913.41 | 3.63 | 3.63 |
| 1171.84 | ||
| 1127.79 | ||
| 1083.74 |