Basic Information
ID: ALA4219412
Type: Binding
Description: Proteolysis targeting chimera activity in human NCI-H661 cells assessed as induction of CRBN/DDB1-mediated delivery of BRD4 for protein degradation by proteasome at 1 uM after 4 hrs in presence of 10 uM thalidomide by Meso Scale Diagnostics assay
Organism: Homo sapiens
Cell type: NCI-H661
Activity Charts
Bioactivity
Activity Types for Assay ALA4219412
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 957.47 | 3.64 | 3.64 |