Assay Report Card

Basic Information

ID: ALA4219413

Type: Binding

Description: Proteolysis targeting chimera activity in human NCI-H661 cells assessed as induction of CRBN/DDB1-mediated delivery of BRD4 for protein degradation by proteasome at 1 uM after 4 hrs in presence of 20 uM MG132 by Meso Scale Diagnostics assay

Organism: Homo sapiens

Cell type: NCI-H661

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
957.473.643.64