Basic Information
ID: ALA4219418
Type: Binding
Description: Proteolysis targeting chimera activity in human MV-4-11 cells assessed as induction of CRBN/DDB1-mediated delivery of BRD4 for protein degradation by proteasome by measuring drug level causing 50% cellular protein depletion incubated for 18 hrs by immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4219418
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 785.28 | 3.68 | 3.68 |