Assay Report Card

Basic Information

ID: ALA4219419

Type: Binding

Description: Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VHL-mediated delivery of BRD4 for protein degradation by proteasome by measuring drug level causing 50% cellular protein depletion incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HeLa

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1002.66