ID: ALA4219519
Type: Binding
Description: Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VCB-mediated delivery of BRD4 short isoform for protein degradation by proteasome by measuring drug level causing 50% cellular protein depletion incubated for 24 hrs by Western blotting method relative to control
Organism: Homo sapiens
Cell type: HeLa
Bioactivity
Activity Types for Assay ALA4219519
Emax
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
923.45 | 5.77 | 5.77 |
1080.75 | ||
1002.66 | ||
958.61 | 5.58 | 5.58 |
1046.71 | ||
992.64 | 7.31 | 7.31 |
1036.69 |