Basic Information
ID: ALA4219524
Type: Binding
Description: Proteolysis targeting chimera activity in human MV4-11 cells assessed as induction of VCB-mediated delivery of BRD4 for protein degradation by proteasome by measuring cellular cMyc protein depletion at 50 nM incubated for 4 hrs by Western blotting method
Organism: Homo sapiens
Cell type: MV4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA4219524
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 434.92 | 6.00 | 6.00 |
| 923.45 | 5.77 | 5.77 |
| 1080.75 | ||
| 1002.66 | ||
| 958.61 | 5.58 | 5.58 |
| 1046.71 | ||
| 992.64 | 7.31 | 7.31 |
| 1036.69 |