Assay Report Card

Basic Information

ID: ALA4220162

Type: Functional

Description: In vivo inhibition of PDK1-mediated PDK1/P70S6K pathway activation in athymic nude mouse tumor xenografted with human AN3CA cells assessed as decrease in phosphorylated s6 protein levels at 50 mg/kg, ip administered daily for 5 days for 2 weeks by Western blot analysis

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
452.473.933.93