ID: ALA4220598
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as N-(6-oxa-2,4-diazabicyclo[3.1.0]hex-3-en-3-yl)-2-chloro-5-(pivalamidomethyl)benzamide formation at 2 uM in presence of 1:1 ratio of unlabeled GSH and [glycine 13C2,15N]-labelled GSH after 0.5 hrs by HPLC-MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsome
Bioactivity
Activity Types for Assay ALA4220598
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
334.81 | 2.98 | 2.98 |