Assay Report Card

Basic Information

ID: ALA4220598

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as N-(6-oxa-2,4-diazabicyclo[3.1.0]hex-3-en-3-yl)-2-chloro-5-(pivalamidomethyl)benzamide formation at 2 uM in presence of 1:1 ratio of unlabeled GSH and [glycine 13C2,15N]-labelled GSH after 0.5 hrs by HPLC-MS analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
334.812.982.98