Basic Information
ID: ALA4221317
Type: Binding
Description: Inhibition of HIV1 reverse transcriptase p66/p51 assessed as freezing of template-primer-enzyme complex at pretranslocated stage at 100 uM using 5'-radiolabeled PBS36c DNA/5'-TTCTGACTAAAAGGGTCTGAGGGAT-3 as template/primer preincubated for 10 mins followed by Fe2+ addition by site-specific foot printing assay
Format: BAO_0000357
Organism: Human immunodeficiency virus 1
Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)
Document: ALA4219091
Inhibition of HIV1 reverse transcriptase p66/p51 assessed as freezing of template-primer-enzyme complex at pretranslocated stage at 100 uM using 5'-radiolabeled PBS36c DNA/5'-TTCTGACTAAAAGGGTCTGAGGGAT-3 as template/primer preincubated for 10 mins followed by Fe2+ addition by site-specific foot printing assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4221317
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 126.00 | -0.16 | -0.16 |
| 346.01 | 1.50 | 1.50 |
| 311.09 | 2.02 | 2.02 |
| 420.39 | 2.21 | 2.21 |
| 426.30 | 2.75 | 2.75 |
| 368.19 | 3.29 | 3.29 |
| 393.16 | 1.30 | 1.30 |