Basic Information
ID: ALA4221469
Type: Binding
Description: Inhibition of sclerostin binding to LRP6 (unknown origin) expressed in rat MC3T3-E1 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in sclerostin-induced inhibition of Wnt3a activation by measuring increase in luciferase activity after 24 hrs by dual-luciferase reporter gene assay
Organism: Homo sapiens
Cell type: MC3T3-E1
Activity Charts
Bioactivity
Activity Types for Assay ALA4221469
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.55 | 5.29 | 5.29 |