Basic Information
ID: ALA4221559
Type: Binding
Description: Inhibition of NPC1L1 in human Caco2 cells assessed as decrease in cholesterol uptake at 100 uM preincubated for 24 hrs followed by stigmosterol substrate addition measured after 24 hrs by HPLC method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4221559
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 637.66 | 5.09 | 5.09 |
| 680.71 | 1.87 | 1.87 |
| 548.51 | 4.20 | 4.20 |
| 564.51 | 4.08 | 4.08 |
| 493.53 | 5.14 | 5.14 |
| 508.57 | 3.74 | 3.74 |
| 651.69 | 5.48 | 5.48 |
| 494.54 | 3.35 | 3.35 |
| 623.63 | 4.70 | 4.70 |
| 694.74 | 2.12 | 2.12 |